This guide focuses on solid-phase extraction (SPE) as a powerful sample preparation technology, utilizing chromatographic packing material to address analytical challenges effectively. SPE is a sample preparation technology utilizing solid particles in a cartridge to chemically separate components of a liquid sample.
Apr 4, 2016 · These include challenges in viral vector-manufacturing capacity, where an estimated 1–2 orders of magnitude increase will likely be needed to support eventual commercial supply requirements for many of the promising disease indications.
May 1, 2022 · In this review, we have discussed the need for sensitivity enhancement in POC devices. Various sensitivity enhancement strategies such as physical, chemical, electrochemical, nanomaterial, nucleic acid, enzymatic, label-based, etc. are discussed along with numerous examples. The role of biosensors in the sensitivity enhancement of POC devices
The following communication rules can improve problem solving: State your problem and interests. Acknowledge others' problems and interests. Avoid name calling and answering a complaint with another complaint. Listen to the other parties and know their interests. Ask “why,” “why not” and “what if” questions to better understand.
Aug 8, 2022 · is also a growing interest in developing nanocarrier-based formulation strategies to enhance the drug absorption. Therefore, this review aims to provide an overview of the challenges faced by oral drug delivery and selected strategies to enhance the oral drug absorption, including the appli-
Formulation Strategies Moving from Intravenous to Subcutaneous and from Vial to PFS. Summary: The biopharma industry continues to look for ways to improve patient compliance through the transition of intravenous (IV) to subcutaneous (SQ) administration and/or vial to pre-filled syringe (PFS) presentation. Both approaches are valuable
Step 1: Establish the Need for a Solution. The purpose of this step is to articulate the problem in the simplest terms possible: “We are looking for X in order to achieve Z as measured by W.”.
Aug 10, 2021 · Action Research Training: Its Effect on the Research Attitude, Knowledge, and Performance of Teachers. Objectives: This study aimed to determine the effect of action research training on the
Jun 11, 2021 · Address online data collection challenges in ethics applications Ethics review boards will vary in their understanding of and tolerance for online data collection. As with face-to-face research, anticipate and address concerns: provide a logic for your study design, explain how the chosen data collection method(s) and platform meet the needs of
Dec 1, 2021 · Besides addressing issues with low metabolite concentrations, another analytical challenge is the study of biological and clinical questions intrinsically dealing with low amounts of starting material, such as exosomes, primary cells, single cell analysis [7], zebra fish, and samples from 3D microfluidic cell culture systems (Fig. 1). Improved
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Mar 5, 2021 · The current trends in modern medicine towards early diagnosis, or even prognosis, of different diseases have brought about the need for the corresponding biomarker detection at ever lower levels in really complex matrices. To do so, it is necessary to use proper extremely sensitive detection techniques such as elemental mass spectrometry. However, target labelling with metals for subsequent
Dec 14, 2021 · Insufficient assessment of the identity and chemical composition of complex natural products, including botanicals, herbal remedies, and dietary supplements, hinders reproducible research and limits understanding mechanism(s) of action and health outcomes, which in turn impede improvements in clinical practice and advances in public health. This review describes available analytical resources
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